CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of the ubiquitin proteasome system in cardiac remodeling, particularly focusing on the 20S proteasome's composition and its regulation during cardiac hypertrophy. The goal is to understand how these changes affect heart disease outcomes.
Heart disease is the number one cause of death in Europe and the world.
Cardiac remodeling involving cardiac hypertrophy is associated with higher morbidity as well as mortality due to heart disease.
Cardiac muscle mass is potentially influenced by the ubiquitin proteasome system (UPS).
At the heart of the UPS is the proteasome, which specifically degrades targeted proteins into peptides.
The candidate has identified that the cardiac proteasomal core, the 20S proteasome, is a heterogenic group o…
UNIVERSITATSKLINIKUM HEIDELBERG
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
