CORDIS Project
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This project aims to enhance the use of enzymes as biocatalysts in organic synthesis by developing automated reaction cascades. It focuses on increasing structural complexity in synthetic pathways, enabling the creation of diverse chemical compounds with potential therapeutic applications.
Enzymes are now established as highly selective biocatalysts in organic synthesis with the range of catalysts and reactions rapidly increasing through access to large protein databases and high-throughput molecular biology tools for biocatalyst engineering.
The diversity of biocatalytic reactions is now at a stage where they can be linked in (chemo)-enzymatic reaction cascades, where two or more chemical and/or enzymatic reactions can be catalysed simultaneously generating de novo biosynthetic p…
THE UNIVERSITY OF MANCHESTER
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