CORDIS Project
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This project aims to create Organ-on-a-Chip models to study preterm birth and its causes, such as environmental toxins and infections. By replicating human physiological conditions, it seeks to identify biomarkers and potential therapies to improve fertility outcomes.
PreTerm Birth (PTB) occurs before 37 weeks of gestation.
Of 60,000 babies born prematurely every year in UK, ~1,400 die.
Premature babies show increased risks of long term neurodevelopmental deficits and chronic diseases.Preterm Rupture of the foetal Membranes (PROM) is a syndrome attributable to multiple factor.
Evidences linked environmental toxicant exposure and infection with a decreased fertility and an increase PTB rate.Studies of these topics suffered for limits of in vitro cell culture (…
UNIVERSITY OF LEEDS
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