CORDIS Project
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This project explores the mechanisms behind liquid-liquid phase separation of proteins linked to neurodegenerative diseases. By combining biophysical methods with molecular simulations, it aims to understand how protein interactions contribute to disease progression and identify potential therapeutic targets.
Neurodegenerative disorders are the leading cause of physical and cognitive disability, currently affecting ~15% population worldwide with estimated global cost of healthcare accosiated with them expected to at least double in the next 20 years.
Five most common neurodegenerative diseases, including ALS and FTD, are linked to formation of protein deposits in patient tissues and are currently without treatment options that would prevent or alter the disease progression. ALS and FTD pathology is c…
UNIVERZA V MARIBORU
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