CORDIS Project
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The PROTAC-PDAC project aims to develop targeted therapies for pancreatic ductal adenocarcinoma using innovative protein degradation technology. It focuses on creating compounds that selectively degrade oncogenic factors to inhibit tumor growth while minimizing toxicity to healthy tissues.
Pancreatic ductal adenocarcinoma (PDAC) is a life-threatening disease with few treatment options.
Recently, the chemical space for targeted therapeutics was significantly increased by the development of compounds that induce protein degradation (PROTACs), but so far, they are unavailable for PDAC.
The main motivation of PROTAC-PDAC is to develop novel targeted therapies for PDAC.
The project is based on our accomplishments in three crucial areas.
First, my group identified – as target candidates…
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
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Germany, Wuerzburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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