CORDIS Project
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This project investigates the chemical processes within protein cages, specifically bacterial organelles, to enhance understanding of confined chemistry. It aims to create artificial protein organelles for controlled enzyme loading and study their interactions within cells, potentially leading to new products or method…
Protein cages appear to be common structures in biology, found in viruses but also in organelle-like containers discovered in bacteria.
In this proposed program I aim to study chemical processes in nano-sized protein cages as mimics of bacterial organelles and to increase the general understanding of chemistry in confinement.Towards this goal we will investigate the controlled in vivo loading of bacterial protein cages, i.e. encapsulins, with proteins and enzymes.
This will allow us to study in…
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