CORDIS Project
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This project utilizes advanced nuclear magnetic resonance techniques to study the dynamics of large proteins and membrane proteins. It aims to link protein motion to their function, particularly in the context of molecular chaperones and substrate transport.
Proteins are highly flexible objects that perform their functions by sampling a wide range of conformations.
The characterization of such motions is, therefore, crucial to establish the link between protein structure and function.
In this project we will use advanced nuclear magnetic resonance in solution state and solid state to characterize functionally important motions in two challenging classes of proteins.The first target of these studies will be a large molecular chaperone of close to 1MD…
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