CORDIS Project
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This project develops a user-friendly kit for analyzing protein N-termini, which are crucial for understanding protein functionality. It aims to make N-terminomics accessible for various laboratories and explore its application in bladder cancer diagnostics by examining proteolytic processes.
Protein N-termini represent a wealth of biological information, such as their generation by limited proteolysis, which sculpts proteome functionality by yielding protein-sized cleavage products with novel functionality. N-terminomics is a branch of functional proteomics and enables the analysis of thousands of protein N-termini in an unbiased manner.
By targeting native, proteolytically generated or acetylated protein N-termini as well as uncovering novel translation initiation sites, N-terminom…
UNIVERSITAETSKLINIKUM FREIBURG
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