CORDIS Project
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This project aims to create non-natural molecules that mimic the alpha-helix structure found in proteins, focusing on their role in protein interactions and functionality. By developing aromatic oligoamide proteomimetics, the project seeks to inhibit protein interactions and restore catalytic activity, potentially lead…
The purpose of this project is to develop a RULE-BASED APPROACH for the design and synthesis of proteomimetics of the alpha-helix and in doing so establish to what extent the structural and functional role of the alpha-helix can be
reproduced with non-natural molecules in a PREDICTABLE manner We will focus on developing aromatic oligoamide proteomimetics (compounds that mimic the secondary structure from which they are derived) of one of the dominant secondary
structural motifs observed in prote…
UNIVERSITY OF LEEDS
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