CORDIS Project
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This project aims to understand the mechanisms behind protein aggregation diseases by studying the cellular responses to misfolded proteins. It seeks to identify potential therapeutic strategies to mitigate the effects of these diseases through quantitative analysis of protein behavior and cellular responses.
Protein aggregation diseases are associated with the intracellular accumulation of specific misfolded protein aggregates, that are directly implicated in cellular dysfunction. A range of human disorders of previously unknown nature now falls into this category.
The mechanisms of aggregation-induced cell degeneration are however unclear, resulting in poor therapeutic strategies.
In this project we will characterize the network of cellular responses to a set of disease-related aggregation-prone pr…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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