CORDIS Project
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ProtEprobe focuses on controlling protein structures using electric fields to study misfolding associated with diseases like Alzheimer's. It aims to enhance tissue regeneration through 3D scaffolds that allow real-time monitoring of protein transitions, potentially improving healing and restoring function in affected t…
ProtEprobe takes advantage of the recent cutting edge developments in protein conformation control at the Malliaras group and high sensitive protein sensing using high sensitivity factor triangular silver nanoplates by the fellow.
Misfolding of a protein occurs when it becomes trapped in a local potential energy minimum where the conformation differs from the native-state structure.
External electric fields have been demonstrated to distinctly alter protein secondary structures.
Proteins associa…
ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT-ETIENNE
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