CORDIS Project
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This project investigates how proteins interact at the molecular level, focusing on the processes of non-specific search and specific recognition in crowded cellular environments. Using advanced simulations and collaboration with experimentalists, it aims to clarify the dynamics and mechanisms behind protein-protein in…
Non-covalent protein-protein interactions underlie most of biological activity on the molecular level. A binding event between two proteins typically consists of two stages: 1) a diffusional, non-specific search of the binding partners for each other, and 2) specific recognition of the compatible contact surfaces followed by complex-formation.
Despite significant progress in studying these processes, a number of open questions remain.
How do partners find each other in the crowded and interac…
UNIVERSITAT WIEN
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