CORDIS Project
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The PSEUDOPIN project investigates the role of pseudouridine in non-coding RNA within plants, focusing on how immune receptor activation influences gene expression. It aims to identify specific pseudouridine sites and their functions in the transition from growth to defense responses using advanced RNA sequencing techn…
Pseudouridine () is abundant in major classes of non-coding RNA (ncRNA), including ribosomal RNA, transfer RNA, and spliceosomal RNAs.
The Watson-Crick base pairing potential of is identical to that of uridine, but may stabilize RNA structures and engage in RNA interactions distinct from those of uridine, probably explaining its requirement for cellular viability.
In addition to the many constitutive -sites in major ncRNAs, recent reports have uncovered induced by specific stimuli or present…
KOBENHAVNS UNIVERSITET
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