CORDIS Project
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This research investigates the connections between the lateral habenula and dorsal raphe nuclei in the brain, focusing on their roles in mood regulation and response to psychedelics. It aims to understand how psychedelics influence these brain regions and their potential in treating depression.
The lateral habenula (LHb) and dorsal raphe nuclei (DRN) are key structures in the brain involved in mood regulation, reward processing, and aversive signaling.
The LHb is a small, yet critical brain region that acts as a major negative regulator of midbrain dopamine systems.
It plays a significant role in processing aversive stimuli and encoding negative reward prediction errors, which are crucial for adaptive behaviors and decision-making processes.
The DRN, on the other hand, is the primary s…
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