CORDIS Project
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This project investigates the role of non-coding DNA in higher organisms, particularly focusing on long non-coding RNA and its effects on gene expression. It aims to understand how pervasive transcription influences the regulation of genes, especially in response to environmental changes in plants.
Genomic DNA represents the blueprint of life: it instructs solutions to challenges during life cycles of organisms.
Curiously DNA in higher organisms is mostly non-protein coding (e.g. 97% in human).
The popular “junk-DNA” hypothesis postulates that this non-coding DNA is non-functional.
However, high-throughput transcriptomics indicates that this may be an over-simplification as most non-coding DNA is transcribed.
This pervasive transcription yields two molecular events that may be functional:…
KOBENHAVNS UNIVERSITET
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