CORDIS Project
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This project investigates the mechanisms of DNA replication and molecular recognition in DNA base pairs using quantum chemical methods. It aims to design monomers for controlled self-organization and enhance understanding of DNA replication processes, contributing to advancements in quantum biology.
DNA replication is at the core of life and strongly appeals to the imagination.
It is also a textbook example of template directed synthesis, involving enzyme-assisted molecular recognition of incoming bases by the template strand.
Yet, in spite of much effort, many fundamental questions about its mechanism are open.
In this research line, using a quantumchemical approach, we aim at two main objectives: (1) understanding the electronic nature of molecular recognition in DNA base pairs, in artifi…
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