CORDIS Project
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This project focuses on enhancing targeted radionuclide therapies for metastatic cancer by investigating the radiobiological effects and mechanisms of treatment. It aims to improve understanding of how these therapies interact with tumor cells, leading to better treatment strategies and patient outcomes.
Background and unmet needTargeted radionuclide therapies (TRTs) are a promising modality to treat patients with metastasized cancer. TRTs function via systemic administration of radiolabelled molecules (α- and β-particle emitters) designed to target tumour cells.
However, the radiobiological effects of TRTs are poorly understood, and rational design of new modalities based on underlying cellular mechanisms is therefore not possible, resulting in suboptimal treatment strategies.
Since most patien…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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