CORDIS Project
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The project investigates the genetic factors contributing to radiation toxicity in cancer patients post-radiotherapy. By analyzing genetic data, it aims to identify variants that predict adverse effects, enhancing personalized treatment approaches.
“Radiogenomics” is the study of the genetics of toxicity following radiotherapy.
Unintended damage to normal tissues can severely affect up to 5% of patients for years after completion of curative cancer radiotherapy.
To date three Genome Wide Association Studies on radiation toxicity in prostate cancer patients have been performed.
These studies have identified genetic loci associated with development of radiation-induced toxicity phenotypes in local tissues.
To increase the very limited power…
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