CORDIS Project
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This project investigates the role of post-translational modifications, particularly arginine methylation, in protein function and gene expression. It aims to identify relevant substrates of Jumonji C histone demethylases using innovative peptide screening technology, enhancing understanding of these modifications in b…
In recent years it has become evident that the functional human proteome is vastly expanded by post-translational modifications (PTMs) that modify protein function and gene expression in a time- and context-dependent manner.
Misregulation of these modifications leads to developmental disorders and often contributes to disease biogenesis.
However, with the possible exception of protein phosphorylation, the full roles and regulation of these modifications remain poorly understood.
Currently, in p…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO
Japan, Tokyo
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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