CORDIS Project
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This research explores how bacteria, specifically Escherichia coli, control their shape and volume. It examines the dynamics of the bacterial cell wall and the role of intracellular crowding in maintaining cell size during growth.
Proper cell size and shape are important for many biological functions, such as metabolism, signaling, motility, and development.
This proposal addresses the fundamental question of how bacteria control their morphology and their cell volume with high precision, using the rod-like bacterium Escherichia coli as a primary model system.
Bacterial cell shape is physically determined during growth by the enzymatic expansion and remodeling of the peptidoglycan (PG) cell wall, a partially ordered elast…
INSTITUT PASTEUR
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