CORDIS Project
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This project investigates how messenger RNA localization and local translation affect protein expression in Drosophila oocytes. It focuses on the role of RNA degradation and translation control in determining cell fate and polarity through the study of specific RNA molecules and their interactions with cellular compone…
mRNA localization and local translation is a common mechanism for efficient protein expression and function control and plays a crucial role in processes such as cell fate determination and polarity and axonal guidance.
One of the better-studied systems for RNA localization is the Drosophila oocyte, in which the microtubule-dependent asymmetric localization of specific transcripts determines the fly body axes. RNA degradation and translational control factors are implicated in mRNA localization,…
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