CORDIS Project
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This project focuses on understanding neuroblastoma, a childhood cancer, by analyzing extensive genetic and molecular data. It aims to uncover the mechanisms behind tumor behavior and treatment resistance, exploring the role of genetic mutations and chromosomal changes in cancer progression.
The successes of cancer research stem from the identification of oncogenes and tumour suppressor genes and the study of their pathways in animal and cell line models.
Confronting these models with ‘real life’ human cancer has often been a challenge.
This grant aims at integral understanding of the aggressive childhood tumor neuroblastoma.
Starting point is a huge database for this tumor.
We established mRNA, miRNA, CGH and SNP profiles for a series of neuroblastoma, and sequenced their whole gen…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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