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The REBUILD project focuses on understanding protein turnover in muscle fibers during aging to address muscle degeneration. By combining genetics and mass spectrometry, it aims to quantify the effects of physical activity on muscle health and develop strategies for maintaining muscle function in the elderly.
During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins.
As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated movements and ultimately to muscle failure in the elderly population.
This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society.
Physical activity is known to delay this decline.The REBUILD project aims to dete…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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