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The REDOX project develops innovative mouse models to monitor reactive oxygen species in living organisms, helping to understand their role in diseases and the effects of oxidative stress. By utilizing advanced genetic technologies, the project aims to clarify the mechanisms of drug and chemical toxicity related to oxi…
Perturbations in cellular redox status are implicated in many human diseases, yet there is an extreme lack of knowledge about the effects of oxidative stress in vivo, mainly due to difficulties in measuring reactive oxygen species (ROS) in vivo and the absence of experimental models.
REDOX will use novel transgenic technologies to develop mouse models that report on ROS in vivo, allowing spatio-temporal monitoring of different types of oxidative stress, ultimately simultaneously in a complex re…
UNIVERSITY OF DUNDEE
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