CORDIS Project
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The Reg-Seq project aims to enhance understanding of Type 2 diabetes by investigating genetic variations in key metabolic tissues. It focuses on identifying both common and rare genetic markers that contribute to the disease, paving the way for personalized treatment strategies.
Type 2 diabetes (T2D) is a complex systemic metabolic disorder which has developed into a global major health problem responsible for early morbidities and mortality. T2D is a multifactorial disease, resulting from progressive alteration of insulin secretion from beta cells in pancreatic islets, on a background of resistance to insulin action in various organs and tissues, including liver, skeletal muscle and adipose tissue. T2D heritability is estimated around 40-70%.
Genome-wide association st…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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