CORDIS Project
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This project investigates the differences in fibroblast biology among salamanders, frogs, and mice to understand their varying limb regeneration abilities. By analyzing fibroblast populations and their responses to regeneration cues, the research aims to uncover the molecular mechanisms that enable or inhibit regenerat…
Limb regeneration capacity varies among vertebrates, ranging from full regeneration in salamanders, to stage-restricted premetamorphic regeneration in frogs, to finger-tip regeneration in newborn mice and humans.The molecular and cellular
basis for these differences in regeneration ability is not known and it is still unclear if these different regenerative events are tied by some common mechanisms with progressive restriction due to extracellular signals or cell intrinsic
changes.Connective tis…
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Germany, Dresden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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