CORDIS Project
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This project investigates spinal cord regeneration in axolotls, focusing on the role of committed neuronal progenitors. It aims to track the fate of these progenitors during regeneration and determine their potential to revert to a more embryonic state.
During spinal cord regeneration in the axolotl, it has been shown that all of the neurons in the regenerate derive from cells near the site of amputation.
It is unknown whether the new neurons derive from a population of multipotent progenitor cells in the mature tissue, or whether committed neuronal progenitors also contribute.
Focusing on committed neuronal progenitors expressing the basic helix-loop-helix (bHLH) family of proneural transcription factors, I will identify the expression patte…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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