CORDIS Project
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REGUBIOME investigates how gut bacteria respond to environmental changes, focusing on one beneficial and one harmful species. It employs innovative methods to explore gene regulation and its implications for host health, aiming to identify targets for microbiome modulation.
Bacteria from the gut microbiota constantly interact with a range of abiotic and biotic factors.
Perturbations in these factors, such as nutrient depletion or exposure to exogenous microbes, require specific bacterial responses that involve tightly controlled gene expression changes.
However, the transcriptional regulation mechanisms promoting such gene expression changes remain poorly understood despite their importance.REGUBIOME will characterize how responses to specific biotic and abiotic st…
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