CORDIS Project
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This project investigates how pancreatic beta-cells regulate insulin release in response to blood glucose changes. It focuses on the movement of large dense core vesicles and the role of motor proteins, aiming to uncover mechanisms that could lead to new treatments for type 2 diabetes.
During meals our bodies break food down into glucose which then moves from the bloodstream into cells to be utilised.
This process requires insulin production by the pancreatic beta-cells.
Impaired function of these cells leads to inadequate insulin output and elevated blood glucose level.
The failure of beta-cells is the main reason for the development of diabetes which affects 22.5 million people in the European Region.
We are interested in the mechanisms by which beta-cells respond to changes…
UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL
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