CORDIS Project
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The project aims to understand the function of CD150-related receptors in the immune system. It will investigate how these receptors influence leukocyte activity and their role in tumor resistance through various experimental approaches.
In order to understand how the mammalian immune system provides protection against pathogens, it is important to understand the molecular basis of immune system function. CD244 is one of the receptors related to CD150 (SLAM) with the potential to bind the adaptors, SAP and EAT-2.
It has recently been shown by the host laboratory that the outcome of engagement of these receptors depends on the context of the interactions, such as which other receptors are engaged, the level of activation, and bet…
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