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REJOIND focuses on developing a method for creating bone tissue in the lab using a bioartificial growth plate. By employing a modular design and computational models, the project aims to guide tissue growth and differentiation, ultimately leading to the production of osteochondral tissues for joint repair and replaceme…
The general aim of REJOIND is to provide proof-of-principle for the in vitro manufacturing of a growing bone, with a bioartificial growth plate as a “driving engine” at its core.
To achieve this, we propose a developmental engineering approach, based on the modular design of in vitro processes consisting of sequential units corresponding to in vivo developmental stages.
These processes follow a gradual and coordinated progression of tissue growth and cell differentiation that leads to organizat…
KATHOLIEKE UNIVERSITEIT LEUVEN
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