CORDIS Project
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This project develops a bone-on-chip model to study osteoporosis by integrating sensors for real-time detection of bone degradation biomarkers. It aims to improve drug screening and disease modeling by creating a more representative environment that mimics bone microarchitecture and osteoclast activity.
Osteoporosis is a common skeletal disorder characterized by imbalanced bone remodeling, where osteoclast activity is exacerbated leading to increased bone degradation and fracture risk.
The socio-economic burden of this disease is elevated in the EU and is expected to further increase in coming years, highlighting the need of improved disease models and drug screening platforms in pre-clinical research.
Organ-on-chip (OoC) technology has been demonstrating high potential to replace anima testing…
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United States, Boston
Type: Research institute
Activity type: Research Organisations
SME: No
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