CORDIS Project
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This project investigates the redox biology and metabolism of endothelial cells, focusing on their role in angiogenesis. By employing advanced imaging and genetic techniques, it aims to uncover the mechanisms of redox signaling and develop new therapeutic strategies for diseases related to abnormal blood vessel growth.
Endothelial cells (ECs) exhibit a remarkable and unique plasticity in terms of redox biology and metabolism.
They can quickly adapt to oxygen, nitric oxide and metabolic variations.
Therefore, EC must be equipped with a selective and unique repertoire of redox and metabolic mechanisms, that play a crucial role to preserve redox balance, and adjust metabolic conditions in both normal and pathological angiogenesis.
The identification of such redox signaling and metabolic pathways is crucial to the…
UNIVERSITA DEGLI STUDI DI PADOVA
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Italy, Torino
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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