CORDIS Project
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This project aims to develop a novel antimicrobial strategy that utilizes self-replicating supramolecular fibers to disrupt bacterial membranes. By leveraging specific bacterial metabolic pathways, it seeks to create targeted and effective antimicrobial agents.
This project aims to address the urgent need for new antimicrobial agents by developing a conceptually new strategy to damage bacterial membranes with supramolecular fibres.Dormant (non-assembling) precursors will accumulate in the membrane of bacteria for in situ switch-on of self-assembly and membrane lysis.
Specific metabolic routes of bacteria, absent in mammalian cells, will be used to transport supramolecular precursors into the membrane of bacteria with full cell specificity.
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UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
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