CORDIS Project
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This project investigates how mitochondria influence the differentiation of T cells by analyzing metabolic pathways and gene expression. It aims to identify mechanisms that link mitochondrial function to T cell responses, with potential applications in treating infections and cancer through immune modulation.
Mitochondria participate during the metabolic reprogramming of naive T cells.
However, the molecular mechanisms by which mitochondria regulate T cell differentiation remain elusive.
The project aims at revealing the mechanisms behind mitochondrial function and lineage specification and maintenance.
Combining high-throughput analysis of gene expression and chromatin epigenetic status with biochemical, metabolic, cellular, and in vivo and in vitro approaches, we want to assess how mitochondria coo…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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