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The RESIST3D project uses patient-derived ovarian cancer organoids to identify strategies for targeting drug-resistant cancer cells. By comparing organoids from pre- and post-chemotherapy samples, the project aims to develop effective treatments that prevent cancer relapse.
Ovarian cancer is the fifth most deadly cancer type among women in Europe.
Despite the fact that standard chemotherapy is usually effective in eliminating bulk tumour mass, thereby inducing remission, most patients diagnosed with advanced ovarian cancer die from the disease, as relapsed lesions emerge from small subpopulations of surviving drug-resistant cells.
Precision medicine aims to improve cancer care through tailoring individualized therapies based on genomic or functional profiling of hu…
KOBENHAVNS UNIVERSITET
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