CORDIS Project
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This project investigates how restoring a healthy lung microbiome can reduce the severity of pneumonia. By using a probiotic made from lung-specific bacteria, it aims to improve treatment strategies that go beyond traditional pathogen-targeting methods.
Nosocomial pneumonia is the second most common and most frequently fatal hospital-acquired infection worldwide.
Previous understanding of lung health depicted a dichotomous view of microbial status (sterile vs. infected), leading to "one-size-fits-all" treatments that primarily target pathogens but neglect the complex host-microbiome interaction.
The RESTORE hypothesis is that re-establishing the healthy respiratory microbiome core using a probiotic composed of lung-specific commensal bacteria a…
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United States, Ann Arbor
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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