CORDIS Project
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This project investigates how changes in gut microbiota after caesarean section may increase the risk of childhood asthma. It aims to identify factors that can restore a healthy microbiome in newborns and explore potential interventions, including fecal microbiota transplantation, to mitigate asthma risk associated wit…
Associations between caesarean section (CS) and childhood asthma may be mediated through microbial changes.
In 700 children followed prospectively from birth, I recently showed that microbial perturbations after delivery by CS explain the delivery mode-associated risk of developing asthma in the first 6 years of life. CS was associated with more than a doubled risk of later asthma and allergic sensitization as well as immense compositional changes in the gut microbiota.
An increased asthma risk…
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