CORDIS Project
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This research focuses on understanding cancer biology through gene regulatory networks in stem and progenitor cells. It aims to identify novel interactions that could inform more effective, tailored cancer treatments based on developmental pathways.
Many genes that have been shown to cause cancer were originally identified because of their role in embryonic development and in the postnatal control of cell growth and differentiation.
The similarities between cancer and development are evident on many levels.
Microscopically, cancerous tissues frequently appear as undifferentiated masses, with some tumor types exhibiting embryonic tissue organization.
The increased mobility of cancer cells, leading to local invasion or metastasis, is reminis…
ISTITUTO NAZIONALE TUMORI Fondazione Pascale
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