CORDIS Project
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The REVEAL project aims to develop an advanced in vitro model to study chronic coughing, which affects many individuals. By creating a human airway-on-a-chip, the project seeks to understand the mechanisms of neuronal hypersensitivity and facilitate drug testing, ultimately improving treatment options for chronic cough…
Coughing is one of the most frequent reasons for physician appointments, and chronic coughing affects one in every 10 people in Europe.
It has severe consequences on the patients’ quality of life.
Treatment options are limited.
Because animal models do not accurately replicate the human disease, the underlying mechanisms that trigger the onset of chronic coughing remain unclear and several promising drug candidates have failed in clinical testing.
Human in vitro models could overcome these hurdl…
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