CORDIS Project
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This project focuses on designing and testing microfluidic chips for studying intrinsically disordered proteins using advanced mass spectrometry techniques. The goal is to streamline the analysis process and enhance understanding of protein conformational changes relevant to biology and pharmaceuticals.
This Fellowship proposal will design, fabricate and test novel microfluidic chips for the study of intrinsically disordered proteins (IDPs) by Hydrogen-Deuterium Exchange coupled with Mass Spectrometry (HDX-MS).
The research program will use thiol-ene polymerisation to form all components of the microchip allowing fast, reproducible and cheap fabrication.
The microchips will incorporate multiple microfluidics channels of varying length and spatially restricted monolith plugs to allow sub-second…
KOBENHAVNS UNIVERSITET
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