CORDIS Project
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This project investigates the role of noncoding circular RNAs in heart failure caused by chemotherapy and COVID-19. It aims to identify and validate these RNA molecules as therapeutic targets to reverse cardiac remodeling and improve treatment options for affected patients.
Heart failure (HF) is a most common cause of mortality with currently >60 million of affected patients.
Numbers will increase due to socioeconomic factors and as a result of the current COVID-19 pandemic. A major underlying cause of HF are cardiac remodelling processes at the molecular, cellular and tissue level.
We will here focus on noncoding circular RNAs (circRNA) involved in two distinct forms of cardiac injury, chemotherapy-induced cardiotoxicity and SARS-CoV-2-infection, where currently n…
MEDIZINISCHE HOCHSCHULE HANNOVER
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