CORDIS Project
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This project aims to develop small molecule mimics of a protein that enhances insulin sensitivity and glucose regulation, targeting type 2 diabetes treatment. By utilizing computational modeling and high-throughput screening, the project seeks to identify potential therapeutic candidates that can improve diabetes manag…
In Europe, 58 million people are living with type 2 diabetes and 36 million people are at risk of developing the condition.
Macrovascular disease is the commonest cause of morbidity and mortality in type 2 diabetes, yet current diabetes therapies have failed to consistently reduce cardiovascular events.
In my Starting Grant, I discovered that a circulating protein, IGF binding protein-1, possesses several favourable characteristics– including insulin sensitisation, amelioration of glucose intole…
UNIVERSITY OF LEEDS
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