CORDIS Project
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The RISK-IR project investigates the cancer risk from low radiation doses by studying the responses of stem cells, which are believed to be the origin of many cancers. It aims to provide a better understanding of how low doses affect cancer risk and individual susceptibility.
The magnitude of cancer risk in humans exposed to low radiation doses (<100mSv) is uncertain and depends upon extrapolation of human population based estimates obtained at higher doses.
The linear non-threshold extrapolation model currently used has some support from mechanistic/biophysical considerations but it is not based on understanding of the biological responses of the cells of origin for radiation cancer.
Stem cells are widely recognised as the cells of origin for many cancers.
Unders…
Department of Health
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UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI
Italy, Caserta
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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