CORDIS Project
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This project investigates how Hox transcription factors interact with mRNA-processing proteins to regulate gene expression during development. By studying these interactions in fruit fly embryos and human cells, the research aims to uncover new mechanisms of gene regulation that could impact our understanding of develo…
Cell fate decisions is governed by the fine-tuned regulation of gene expression in all living organism.
It is mostly realized by the cell-type specific assembly of regulatory networks consisting of Transcription Factors (TFs) and cofactors proteins.
Thus, a multitude of combination between TF and cofactors will be set up to regulate the transcription in a precise spatiotemporal manner.
The evolutionary conserved class of Hox TFs perfectly illustrates how a restricted number of TFs is able to pro…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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