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The RNACOM project investigates how gastrointestinal parasites, particularly helminths, use ribonucleic acids to communicate with host cells, influencing gut health and immune responses. It aims to uncover the mechanisms of this RNA communication and develop strategies to disrupt it during infections.
Cross-species communication is required for proper functioning of the mammalian gut, where different organisms share resources, coordinate digestion and maintain homeostasis.
In many animals, parasitic worms (helminths) are part of this ecosystem, where they communicate through the release of bio-active molecules that promote immunological tolerance and modulate gut functions.
Mechanisms of cross-species communication are still not well understood and my lab discovered that ribonucleic acids (RN…
THE UNIVERSITY OF EDINBURGH
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