CORDIS Project
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This project explores the role of sebaceous glands in skin inflammation and lipid metabolism. It aims to identify genetic programs that regulate these functions, potentially leading to new therapeutic strategies for skin diseases.
In the pathogenesis of dermal inflammation, sebaceous glands (SGs) were considered as impotent players that are under the control of other cell types, but without any feedback on them.
Only research of the past decade put SGs into our focus showing that besides their contribution to the lipid layer covering the skin surface and the hair, SGs are also capable of exerting inflammatory responses, thus providing an interesting cell type where lipid metabolism and inflammation is linked at a cellular…
KAROLINSKA INSTITUTET
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