CORDIS Project
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This proposal investigates the connections between the nervous and vascular systems, particularly how angiogenic factors influence neuronal development. The research aims to uncover the molecular mechanisms behind neurodevelopmental processes, potentially informing treatments for related disorders.
Despite their distinct functions, the nervous and vascular systems share many more similarities and common principles than previously anticipated2.
For example, factors involved in the development of the nervous system are also known to regulate blood vessel formation3.
Conversely, the key angiogenic factor, vascular endothelial growth factor (VEGF-A, termed from hereon VEGF), as well as other members of its family such as VEGF-C and VEGF-D, and their receptors, are expressed in neuronal cells a…
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
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