CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of specific enzymes, histone deacetylases 5 and 9, in the differentiation of blood cells. Using genetic models, it aims to uncover how these enzymes influence gene expression and cell commitment in hematopoietic stem cells, contributing to advancements in regenerative medicine.
Chromatin, the higher order structure of DNA and protein, forms a barrier for gene transcription.
Modification of histones, a major component of the chromatin, is a critical mechanism by which the barrier is regulated.
An important modification, which is thought to activate transcription, is the acetylation of histones.
Regulation of histones acetylation is performed by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs).
Mammalian HDACs are divide…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
