CORDIS Project
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This project investigates how the dynamics of mitochondria influence the migration and development of T cells in the thymus. By studying the balance between mitochondrial fusion and fission, the research aims to uncover their roles in T cell behavior and immune system development.
Mitochondria are highly dynamic organelles that continuously move, divide and fuse in a highly regulated fashion.
The balance between the opposing processes of mitochondrial fusion and fission is controlled by a growing family of “mitochondria-shaping” proteins.
Evidence is accumulating on the role of these proteins in several functions, from apoptosis to Ca2+ signaling, to morphogenesis of dendritic spines and synapses, to regulation of migration of leukocytes.
The knowledge of the regulation o…
UNIVERSITE DE GENEVE
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